The End of Statin Drugs?
A paper co-authored by Beatrice Golomb, MD, PhD, associate professor of medicine at the University of California, San Diego School of Medicine and director of UC San Diego’s Statin Study group cites nearly 900 studies on the adverse effects of HMG-CoA reductase inhibitors (statins), a class of drugs widely used to treat high cholesterol.
The result is a review paper, currently published in the on-line edition of American Journal of Cardiovascular Drugs, that provides the most complete picture to date of reported side effects of statins, showing the state of evidence for each. The paper also helps explain why certain individuals have an increased risk for such adverse effects.
“Muscle problems are the best known of statin drugs’ adverse side effects,” said Golomb. “But cognitive problems and peripheral neuropathy, or pain or numbness in the extremities like fingers and toes, are also widely reported.” A spectrum of other problems, ranging from blood glucose elevations to tendon problems, can also occur as side effects from statins. Read the full article in eurekalert.org
I also found this multi parts Talk on cholesterol and statin drugs by Paul Rosch, MD, about the Dangers of Cholesterol-Lowering Drugs and the myths of Cholesterol. He focuses on the subtle yet serious and unappreciated dangers of cholesterol-lowering measures using statin drugs based on current guidelines due to confusion about the mechanisms that mediate their cardioprotective effects. You can find the links to the other parts after you watch the first part.
Links:
Read the full article in eurekalert.org
Talk on cholesterol and statin drugs
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I appreciate the information on statins that you presented. I’ve heard of many individuals taking statins who develop problems. I never understood the connection between muscle problems and statins until reading this post. Thanks!